Non-Alcoholic Fatty Liver Disease — An Epidemic of the New Millennium

نویسنده

  • RAJESH UPADHYAY
چکیده

Non-alcoholic fatty liver disease (NAFLD) represents a spectrum of conditions characterized by macrovesicular hepatic steatosis in the absence of significant alcohol intake (less than 20 gm/day for males and 10 gm/day for females). Two main histological patterns are recognized: 1. Steatosis without inflammation; and 2. steatohepatitis (NASH) with inflammation, fibrosis and cirrhosis. NAFLD is also divided into two types. Primary NAFLD refers to fatty liver associated with metabolic syndrome (obesity, type 2 diabetes, hyperlipidemia and insulin resistance). On the other hand, secondary NAFLD includes fatty liver disease with a proximate cause (Table 1).

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تاریخ انتشار 2007